Natto LP

There is a natural substance in the blood called fibrinogen. If there is trauma or injury to a blood vessel the fibrinogen is converted to fibrin. Fibrin is a sticky protein that adheres to the walls of the blood vessel. As blood cells and platelets arrive they begin to stick to the fibrin to form a blood clot and stop the bleeding.

Enzymes are universally used throughout the body and life cannot exist without them. A systemic enzyme is an enzyme that supports your circulatory system. If they are in your digestive system they are called digestive enzymes, if they are in your blood stream, they’re called systemic enzymes. There is a natural substance in the blood called fibrinogen. If there is trauma or injury to a blood vessel the fibrinogen is converted to fibrin. Fibrin is a sticky protein that adheres to the walls of the blood vessel. As blood cells and platelets arrive they begin to stick to the fibrin to form a blood clot and stop the bleeding. Unfortunately, blood may also clot when platelets adhere to fibrin on fatty plaque of atherosclerosis, and create an unnecessary blood clot over time. When tissues are starved of proper blood flow they will begin to weaken and die. Fibrinolysis is the process of dissolving blood clots. Fibrinolysis is achieved by an enzyme called plasmin. As our bodies age, production of enzymes begins to decline. An unhealthy production level of these enzymes can lead to the development of blood clots, and the health imbalances caused by them. Other factors such as bacteria, viruses, and toxins in the blood can cause inflammation resulting in cross-linked fibrin that can circulate in the blood and stick to the walls of blood vessels. Narrowing blood vessels and increased blood viscosity (thickness) contribute to increased blood pressure and other health imbalances.

Nattokinase has shown to have a high fibrinolytic activity (breaks down fibrin). It also helps dissolve existing blood clots (thrombus) by dissolving the fibrin that binds platelets and red blood cells together.

An enzyme in the body called angiotensin converting enzyme (ACE) helps synthesize angiotensin II which raises blood pressure by constricting blood vessels. Hypertension is often treated with ACE inhibitors to help lower the level of angiotensin II. Nattokinase has been shown to lower blood pressure levels by inhibiting angiotensin converting enzyme (ACE).

Nattokinase has also been shown to support blood circulation by assisting in the clearing of circulation and preventing hardening of the arteries.

The Importance of Protease and Lipase

Enzymes are the metabolic driving force throughout the entire body. Proteolytic and Lipolytic enzymes are able to break down proteins, fats, toxins, and cellular waste in the blood stream and throughout the body. A healthy blood stream maximizes nattokinase enzymes to function at full potential.

Proteolytic enzymes break down protein and are often referred to as proteases. These enzymes help the body’s immune system break down toxins, foreign proteins, pathogens, and dead cells. This helps reduce stress off of other body systems. They also help balance the body’s pH level.

Lipolytic enzymes break down fat. Poor fat and lipid metabolism can lead to cardiovascular imbalances because fats are a major source of fuel for the heart and brain. A healthy person’s body is between 20-24% fat cells. Yet some fats and lipids such as triglycerides can harm our cardiovascular system. Lipase can help control triglyceride and LDL cholesterol levels.

What is Nattokinase NSK-SD™?

Nattokinase is found in Natto, a food derived from soybeans.

References:
1. H. Sumi, H. Hamada, H. Tsushima, H. Mihara, A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese natto; a typical and popular soybean food in the Japanese diet, Experimentia 1987, Oct 15;43(10);1110-1.
2. M. Maruyama, H. Sumi, Effect of Natto Diet on Blood Pressure, JTTAS, 1995.
3. Sumi H. Healthy Microbe “Bacillus natto.” Japan Bio Science Laboratory Co. Ltd.
4. Lipids 32: 1147, 1997

The Natto-LP is formulated to work synergistically with the body to assist in fibrin, protein, fat and carbohydrate digestion in the blood. Take a look at the relationship between various conditions and the blood.

Nattokinase has been the subject of 17 studies. Dr. Sumi’s first clinical trial with humans included 12 volunteers. They were administered 200 grams of Natto (the food) each day. Two types of measurement methods were used to test fibrinolytic activity. The Euglobulin Clot Lysis Test stimulated an artificial thrombus (blood clot) within the volunteer’s blood sample. Then they measured the time it took for the clot to completely dissolve. The amount of time it took for the blood clot to dissolve in the Natto group dropped by 48% within 2 hours. An additional study showed an 11% decrease in blood pressure after 2 weeks.

A clinical trial involving dogs was also conducted by Dr. Sumi. Two groups of dogs were used. One group received nattokinase, and the other group received a placebo. A blood clot (thrombus) was created in a leg vein of each dog. The dogs that had nattokinase in their diet had no blood clots within 5 hours. The dogs that were fed placebos still had the blockage caused by the blood clot 18 hours later.

Phase Contrast Live Blood Conditions

The Natto-LP is a systemic enzyme formulated to work synergistically with the body to assist in fibrin, protein, fat and carbohydrate digestion in the blood. It is the strongest fibrinolytic, proteolytic, and lipolytic enzyme formulation on the market. Take a look at what undigested substances in your blood can do to your cardiovascular system.*

Normal Red Blood Cells
Notice how the erythrocytes (blood cells) are round and separated. This allows the blood to flow smoothly through blood vessels and capillaries and into cells to provide oxygen, nutrients, antibodies, and hormones.*

Protein Linkage
Protein Linkage occurs when excess undigested protein and fat in the blood coats the red blood cells and causes them to stick together. This increase blood viscosity (thickness) and stress on the circulatory system.*

Rouleau
Rouleau results from a large amount of undigested protein and fat in the blood. Notice that the red blood cells are stacked like coins. This reduces their surface area and the amount of oxygen that can be carried by them.*

Erythrocyte Aggregation
Erythocyte Aggregation results from a large amount of undigested proteins and fats in the blood. Notice the red blood cells all bunched together. This reduces their ability to carry oxygen and vital nutrients. It also increases blood viscosity (thickness), increasing stress on the circulatory system.*

Fibrin
Fibrin may resemble a spider web. It is part of the blood clotting mechanism, however, fibrinogen shows up in the blood when the there are toxins present indicating inflammation. It may indicate improper elimination, and liver stress.*

Cholesterol Crystal
Cholesterol Crystals result from excess undigested fats not being cleared from the blood. Notice the crystal appears milky or clear.*

Thrombocytes
Platelets are what makes the blood clot when there is an injury. This is what stops the bleeding if you cut yourself. Large amounts of platelets may appear in the blood when there is inflammation or injury.*

Thrombocyte Aggregation
Thrombocyte Aggregation results from platelets sticking together in large masses due to excessive proteins, fats, or sugars.*

Plaque
Cooked/processed fats and platelets sticking together and hardening, sometimes it sticks to the inside of blood vessel walls.*

Chylous
Small grayish dots in the blood known as blood fats. Chylous usually shows up after a fatty meal but should be gone within 3 to 5 hours.*

References:
1. H. Sumi, H. Hamada, H. Tsushima, H. Mihara, A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese natto; a typical and popular soybean food in the Japanese diet, Experimentia 1987, Oct 15;43(10);1110-1.
2. M. Maruyama, H. Sumi, Effect of Natto Diet on Blood Pressure, JTTAS, 1995.
3. Natto-Traditional Japanese Fermented Soy Beans with Recently Discovered Health Benefits and Novel Industrial Applications, Enzyme Wave, Volume 3, June 2002, Amano Enzyme, Inc., page 2-4.

Blood Under the Microscope
Enzymes act as scavengers of foreign substances throughout the body. Enzymes in the body’s white blood cells are responsible for destroying foreign, disease-producing substances in the blood and lymph. During illness and infection, white blood cells increase to fight off pathogens. When cooked foods are eaten, the body reacts just as though we had an acute illness. Within 30 minutes of eating cooked foods, our white-blood-cell count increases dramatically. This means that the immune system is being unnecessarily called into action virtually every time we eat.

Studies show that mobilization and increase of white blood cells do not happen when raw food is consumed. Molecules from improperly digested proteins and fats that are small enough to get into the blood, but too large to get into the cells, are called floating immune complexes. They are now considered toxic invaders in the body instead of nutrients.

The dark field microscope is a viable technology used for live blood analysis. This microscope can magnify a tiny drop of blood 15,000 times and can give an accurate picture of floating immune complexes. Let’s take a look at some of the unhealthy conditions we can see under this microscope. We see red blood cells sticking together, which results in a lack of surface area and creates low oxygen content. This can lead to chronic fatigue, migraine headaches, and poor circulation. We see cholesterol and uric acid crystals, which could eventually lead to arthritis or gout. We see plaque due to undigested fats, which can lead to arteriosclerosis. We see free radical damage, which can have devastating consequences. It takes a concentrated effort from white blood cells to digest floating immune complexes and protect our body from other toxic invaders. Meanwhile , he organs, tissues, and glands are robbed of their rightful share of needed enzymes.